Modafinil est fabriquГ© par et Г partir d'AstraZeneca. L'approbation Г©tait basГ©e sur un essai clinique rГ©ussi Г grande Г©chelle. Le modafinil Г 200 mg est la forme la plus courante du mГ©dicament et est indiquГ© pour le traitement de la narcolepsie. Le modafinil se trouve aux Г‰tats-Unis en capsules de 200 mg, 300 mg, 400 mg et 500 mg.
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Avant l'approbation du mГ©dicament pour un usage mГ©dical, une sГ©rie d'Г©tudes sur le comportement humain ont rapportГ© que le modafinil amГ©liorait l'attention et la mГ©moire chez des volontaires sains et des personnes atteintes de troubles neurologiques tels que le trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH). Modafinil n'a pas de propriГ©tГ©s de libГ©ration contrГґlГ©e. Le modafinil peut ГЄtre utilisГ© dans le traitement d'autres troubles du sommeil. Au Royaume-Uni, le modafinil est prescrit sous le nom d'Armodafinil et vendu sous le nom commercial Provigil. Le modafinil peut stimuler la libГ©ration de dopamine, de noradrГ©naline et d'acГ©tylcholine.
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