Selon la condition pour laquelle la prescription a Г©tГ© rГ©digГ©e, l'assurance peut ou non couvrir le modafinil. Il est aussi parfois utilisГ© en complГ©ment d'un traitement aux amphГ©tamines comme le modafinil qui est pris avec une amphГ©tamine, mais l'association n'est gГ©nГ©ralement pas recommandГ©e. Le modafinil Г©tait commercialisГ© sous le nom de Provigil pour les humains et d'Orudis pour les animaux. Il est excrГ©tГ© sous forme inchangГ©e dans les urines. Certaines des premiГЁres donnГ©es les plus prometteuses sur l'utilisation du modafinil pour augmenter la fonction cognitive proviennent d'une Г©tude qui a montrГ© une amГ©lioration cognitive chez les patients atteints de la maladie d'Alzheimer modГ©rГ©e Г sГ©vГЁre.
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Les patients doivent ГЄtre avertis que Modafinil ne fonctionnera pas pour les personnes qui ne se portent gГ©nГ©ralement pas bien lorsqu'elles prennent un stimulant. Les effets secondaires les plus courants Г©taient l'insomnie, les maux de tГЄte, les nausГ©es et les rГЄves altГ©rГ©s, signalГ©s par 10 % Г 36 % des patients. Le modafinil est un agent thГ©rapeutique sГ»r et efficace pour le traitement de la somnolence diurne excessive dans la narcolepsie. Au moment de la dГ©couverte de Jouvet, le modafinil Г©tait beaucoup moins sГ©lectif que l'amphГ©tamine ou ses dГ©rivГ©s. Le modafinil augmente l'Г©veil, ce qui est le contraire de la somnolence.
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